The Institute of International Studies Ramkhamhaeng University (IIS-RU) was established in 1999. The institute offers three Bachelor's Degree programs: B.A. in English, B.B.A. in Global Business and Digital Age Entrepreneurship, and B.A. in Media and Global Innovative Communication. All programs are designed as three-year curriculums to facilitate quicker graduation.

Internationalization is one of the key strengths that IISRU embraces, with a significant proportion of international students, representing diverse backgrounds from over 16 countries. This diversity enriches the classroom experience and various activities.

The institute has established MOUs with partners from Germany, France, Switzerland, Japan, and other countries to create exchangeable semesters for both inbound and outbound students.

Looking ahead, IIS-RU aims to introduce a Master's Degree program in business to provide more variety and broaden the study options available.